Impact of Long-Term Serum Platinum Concentrations on Neuro- and Ototoxicity in Cisplatin-Treated Survivors of Testicular Cancer [Urologic Oncology]
Conclusion
Here we document a significant relationship between increasing levels of residual serum platinum and NTX severity after adjusting for initial cisplatin dose. (Source: Journal of Clinical Oncology)
Insular lateralization in tinnitus distress.
Authors: van der Loo E, Congedo M, Vanneste S, De Heyning PV, De Ridder D
Abstract
Tinnitus affects 15% of the population. Of these 1-2% are severely disabled by it. The role of the autonomic system in tinnitus is hardly being investigated. The aim of this study is to investigate the relationship between tinnitus distress and lateralization of the anterior insula, known to be involved in interoceptive awareness and (para)sympathetic changes. For this, Tinnitus Questionnaire scores are correlated to Heart Rate Variability markers, and related to neural activity in left and right anterior insula. Our results show that tinnitus distress is related to sympathetic activation, in part mediated via the right anterior insula.
PMID: 21889914 [PubMed - as supplied by publisher] (Source: ...
Noise Exposure Can Cause Long-Lasting Changes To Sensory Pathways; Touch-Sensing Nerve Cells May Lead To Future Tinnitus Treatments MedWorm Sponsor Message: Find the best January Sales in the UK.
We all know that it can take a little while for our hearing to bounce back after listening to our iPods too loud or attending a raucous concert. But new research at the University of Michigan Health System suggests over-exposure to noise can actually cause more lasting changes to our auditory circuitry - changes that may lead to tinnitus, commonly known as ringing in the ears... (Source: Health News from Medical News Today)
Tinnitus: where is the source (Commentary on Vanneste et al.)
(Source: European Journal of Neuroscience)
Clinical and Radiologic Findings of Inner Ear Involvement in Sickle Cell Disease [HEAD & NECK]
CONCLUSIONS:LH and LO were found in approximately one-third of patients with SCD with inner ear symptoms and preferentially affected males. (Source: American Journal of Neuroradiology)
Tinnitus severity and its association with cognitive and somatic anxiety: a critical study
Abstract Tinnitus has been defined as a phantom auditory perception. Research indicates the necessity to make a distinction between
the physical symptom and the subjective severity of the tinnitus symptom, since especially the latter seems to vary among
patients. The relationship between tinnitus severity and psychological variables has been well established. Anxiety is considered
to be an important variable for understanding the differences in the subjective tinnitus severity. Although many studies confirm
the relationship between anxiety and tinnitus severity, most studies do not take the possibility of shared method variance
and content overlap between questionnaires into account. Furthermore, anxiety is a broad concept and contains both a cognitive
and somatic dimensio...
Short duration repetitive transcranial magnetic stimulation for tinnitus treatment: A prospective Asian study MedWorm Sponsor Message: Find the best January Sales in the UK.
Conclusions: Our findings point to a positive effect of short duration rTMS in tinnitus treatment using the THI. However, no significant benefits were demonstrated for other subjective patient ratings. Although well tolerated and convenient, short duration rTMS may prove inadequate for modulating maladaptive plastic changes at the cortical level, and our results suggest the need for delivery of more stimuli. Future studies will utilize at least 2000 pulses/day, in line with previous experience in Western settings. (Source: Clinical Neurology and Neurosurgery)
Tinnitus complaint behaviour in long‐standing Menière’s disorder: its association with the other cardinal symptoms
Conclusion: Tinnitus shares a significant variance with the other cardinal symptoms in patients with long‐standing Menière’s disorder. As the impact is significantly related to activity limitations based on hearing disability and vertigo, the results suggest that therapeutic efforts to reduce tinnitus in Menière’s disorder should include the alleviation of balance and hearing problems. (Source: Clinical Otolaryngology)
